CBD Science, LLC , and its parent company, Coles & Company, LLC provides research, education and consulting services to individuals and companies in the Cannabis and Hemp industries.

Our mission is to help entrepreneurs and established companies help the most amount of people in the least amount of time.  We offer Intellectual property for extraction, processing, and marketing of proprietary products.

Our expertise is “Synergistic Science” as articulated by R Buckminster Fuller.   Synergistics provides a rigorous framework for understanding Phyto cannabinoids present in nature and their interaction with the Endo Cannabinoid Systems (ECS) present in all vertebrates.

Our three patents provide industry participants with protection from Big Pharma. The first is entitled “Systems and Methods for Producing Organic Cannabis Tinctures”. If covers both hot and cold organic extraction of all stages of the plant (acid, neutral and metabolite) and produces specified doses for effective utilization

Our second patent is  for creating remedies for specific indications as well as “treatment resistant conditions” such as fibromyalgia, IBS and Chronic pan. Our third patent is for “cannabinoid therapy” to for treating Clinical Endo Cannabinoid Deficiency (CECD)

For additional information email albert.coles@mail.com or call 415-407-0508 and ask for Al.

For more information contact Albert L Coles, Jr. 415-407-0508i



We introduced a “smokeless" alternative with “specified” dosages for medical marijuana patients in 2010.   In 2011, I provided the CBD tinctures to the team at Harborside Health Center that successfully treated the first case of Dravets syndrome (seizures) in a 4-year-old boy named Jayden.

 Through research and collaboration with my son Albie, we were the first to offer Non-psychoactive Medicinal Cannabinoid tinctures to relieved symptoms of Pain (THCA and CBDA)), Anxiety (CBD) and Insomnia (CBN).

 CBDScience.com offers a rigorous alternative view of how cannabinoids work.

Our paper “Yin/Yang…. Excerpts for the CBD Science Guide to Medical Marijuana was the first to articulate how THC and CBD operate.


Professor Raphael Mechoulam of Medicinal Chemistry and Natural Products at the Hebrew University, describes cannabinoids as anti-inflammatory for arthritis, as neuroprotectant for brain injury and as a possible treatment for PTSD.

SC Laboratories describes ‪cannabinoid profiles including THC, THCA, THCV, CBD, CBG, CBN, CBC and terpenes‬.

"We are currently determining the molecular mechanism that may explain the synergistic increase in anticancer activity that is observed with the combination treatments". 
- Sean D. McAllister, PhD., Researcher at California Pacific Medical Center Research Institute