August 12, 2013                         

Medical Marijuana Company Celebrates 3rd Anniversary with “Weed”
hosted by Dr. Sanja Guptas on CNN

“It couldn’t have been a better anniversary present,” said Albert Coles, Jr., founder and lead researcher at CBD Science, LLC. “Right there on CNN, Sanja Gupta told the story about a child whose family I helped get the right cannabinal formula that stopped the shakes (epileptic seizers).” 

Coles, who has a background in investment finance, said, “It’s not the big money I thought it was going to be, but I keep developing formulas because it helps people big-time.” He continued, “That’s the real paycheck. Gupta’s bomb shell (“Weed” aired 8/11/13 on CNN) last night woke up thousands of doctors and patients that medical cannabis is for real.”

Founded in 2010, CBD Science, LLC in Stinson Beach, California is a consultancy and developer of formulas for Cannabis Based Medical Extracts (CBMEs) for licensed dispensaries and patient cooperatives in California. The most popular is the Alta California Botanicals™ brand sold in three formulations at licensed retailers: “Healing Tincture” with high CBD and low THC, “Tranquility Tincture” with 1:1 ratio of CBD to THC, and “Euphoria Tincture” with low CBD and high THC. 

“Next year will be a tipping point,” Coles said, “Twenty states and the District of Columbia have now voted to approve marijuana for medical applications.  Sativex® by GW Pharmaceuticals will soon be approved by the FDA as a prescription drug. That will convince the medical community to how remarkably well cannabinoids can be used to treat systemic diseases and neurological disorders.”

“We are in this for the long haul,” Coles said. “CBD Science is committed to the latest scientific data and testing while operating strictly within the laws of California. We have more new formulas in the pipeline. The future looks brighter today then ever before.”

“Weed”: A Dr. Sanjay Gupta Special:
“Why I Changed My Mind on Weed”, Dr. Sanjay Gupta, CNN Chief Medical Correspondent, August 8, 2013,
CBD Science, LLC:
Alta California Botanicals, LLC:
GW Pharmaceuticals:

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Press Release April 10, 2011
CBD Science, LLC has developed three Cannabis Based Medicinal Extracts (CBME), now available in selected California dispensaries. Branded Alta California, the CBMEs are derived from organic plant material and offer patients a choice of a low, medium or high euphoric component (THC), balanced with the healing element (CBD). 

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San Francisco, Calif. (PRWEB) May 10, 2011
CBD Science LLC has developed three Cannabis Based Medicinal Extracts (CBME), now available in selected California dispensaries. Branded Alta California, the CBMEs are derived from organic plant material and offer patients a choice of a low, medium or high euphoric component (THC), balanced with the healing element (CBD). Product information is available atThese are the first CBME products on the market with certified potency and purity, scientifically calibrated and documented. Steep Hill Lab certifies the CBMEs as Safe Cannabis™, free of pesticides and mold. The lab also documents the potency. Alta California CBME products are available to patients with valid recommendations at the following non-profit dispensaries:  SPARC and in San Francisco and Harborside in Oakland, California.

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Why Most Tinctures Don’t Work, Albert L. Coles

I’ve tried tinctures and they don’t work. There are two reasons why most tinctures don’t work:

1) The first reason is the potency of the tincture. Shocking, but true, most of the tinctures in dispensaries do not contain sufficient medicine (THC and or CBD) to generate the experience that patient’s desire. All but two of the tinctures we surveyed in the fall of 2010 failed to provided enough medicine for the desired experience at a reasonable price. I am confident that this is not an intentional attempt to mislead or rip anyone off. The reason is simple; it was not possible to know what the THC content was in tinctures that contain organic compounds (oil/ glycerin/ butter etc.) until laboratories such as Steep Hill in Oakland starting testing for potency using Liquid Chromatography.

2) The second reason is your “bioavailability”. This is your capacity to absorb the medicine. Your capacity to absorb the medicine is primarily dependent upon the contents in your stomach. Have you ever eaten a Cannabis “brownie” by mistake on an empty stomach and found yourself an hour later pondering the existence of the universe? Or have you ever eaten a brownie intentionally to “get high” on a full stomach and didn’t “feel anything”. The differences in these experiences are a function of the contents of your stomach and your expectations.

Your expectations are determined by more subtle factors than the contents of your stomach. Timothy Leary advised us 40 years ago, that the nature of the “experience” depends primarily on “set” and “setting”:

Set denotes the preparation of the individual, including personality structure and mood at the time.

Setting is physical - the weather, the room's atmosphere; social - feelings of persons present towards one another; and cultural - prevailing views as to what is real.

Below is a chart summarizes the results of our survey of tincture potency. All of the testing was done by Halent Steep Hill Labratories, Oakland, California. In some cases they were so surprised by the results and repeated the tests multiple times. 



March 11, 2014

Medical Marijuana and 'The Entourage Effect'
By Dr. Sanjay Gupta

There are more than 480 natural components in the cannabis plant. The entourage effect" means those components may work best together.

Read Article >>

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Weed2 Cannabis Madness 
by Dr. Sanjay Gupta

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Dr. Sanjay Gupta explains why THC and CBD work better together than separately in their "pure" or synthetic forms.

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"Guide to Medical Marijuana"  CbD Science explains the effective use of  cannabinoids for treating specific diseases and related symptoms. 



Download File

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Cannabis News - Medical Marijuana, Hemp, Marijuana News, Cannabis

Study shows non-hallucinogenic cannabinoids are effective anti-cancer drugs 14 October 2013
St George's, University of London 

New research has shown that the non-hallucinogenic components of cannabis could act as effective anti-cancer agents.

The anti-cancer properties of tetrahydrocannabinol (THC), the primary hallucinogenic component of cannabis, has been recognised for many years, but research into similar cannabis-derived compounds, known as cannabinoids, has been limited.

The study was carried out by a team at St George’s, University of London. It has been published in the journal Anticancer Research.

The team, led by Dr Wai Liu and colleagues carried out laboratory investigations using a number of cannabinoids, either alone or in combination with each other, to measure their anti-cancer actions in relation to leukaemia.

Of six cannabinoids studied, each demonstrated anti-cancer properties as effective as those seen in THC. Importantly, they had an increased effect on cancer cells when combined with each other.

Dr Liu said: “This study is a critical step in unpicking the mysteries of cannabis as a source of medicine. The cannabinoids examined have minimal, if any, hallucinogenic side effects, and their properties as anti-cancer agents are promising.

“These agents are able to interfere with the development of cancerous cells, stopping them in their tracks and preventing them from growing. In some cases, by using specific dosage patterns, they can destroy cancer cells on their own.

“Used in combination with existing treatment, we could discover some highly effective strategies for tackling cancer. Significantly, these compounds are inexpensive to produce and making better use of their unique properties could result in much more cost effective anti-cancer drugs in future.”

This latest research is part of a growing portfolio of studies into the medicinal properties of cannabis by the research team at St George’s. The next step will be to examine in the laboratory these compounds in combination with existing anti-cancer treatments and study treatment schedules to identify strategies that will maximise their efficacy.

The study examined two forms of cannabidiol (CBD), two forms of cannabigerol (CBG) and two forms of cannabigevarin (CBGV). These represent the most common cannabinoids found in the cannabis plant apart from THC.

Full bibliographic informationEnhancing the Activity of Cannabidiol and Other Cannabinoids In Vitro Through Modifications to Drug Combinations and Treatment Schedules 

(1) This survey was complied by Albert L Coles, Jr. of 420 Alchemy, LLC, call 877-737-4420 or 415-868-2160 or go to
(2) Chronic Tonic : 420 Alchemy, LLC: tested to be 10% mg ml.
(3) Breath Spray: Green Cross: tested to be 8% mg/ml
(4) Medicinal Cannabis: Northstone 1 oz B grade outdoor for $230, 1 joint for $8.17: Amount of THC per joint refer to:
"Medicinal Cannabis: Rational Guidelines for Dosing" 2004: Refer to
(5) Marinol: Solvay Pharmaceuticals (recently acquired by Abbot Labs)
refer to "Marijuana vs. Marinol" go to
(6) Totally Baked: Hampton Collective: tested to be .27 mg/ml.
(7) Dr. Chin: Grass Roots: tested to be .383 mg/ml.
(8) Pocket Alchemy: DNA: tested to be .18% mg/ml.
(9) Cannabis Medicinals of California: "Triple X" tested to be .05% mg/ml.
(10) Total THC mg: test result multiplied by amount: for instance 10 X 30 = 300.
(11) Average Dosage refer to "Medicinal Cannabis: Rational Guidelines for Dosing" 2004.
(12) Cost per mg of THC: cost/total THC mg/ml: for instance 60/300 = .2
( 13) Daily Dosage refer to "Medicinal Cannabis: Rational Guidelines for Dosing" 2004.