CBDA - Cannabidolic Acid
CBDA is the main constituent in raw cannabis. CBDA converts to Cannabidol (CBD) when burned, vaporized, or heated for a period of time at a certain temperature. CBDA has no psychoactive effects, it contains
Anti - Bacterial
properties that are lost when the plant is heated
CBDA not only has anti-proliferative abilities that are crucial in helping inhibit the growth of cancerous cells, but also, it has anti-spasmodic abilities that helps subdue muscle spasms and therefore has potential use among epileptic patients.
CBDA has been shown to be more effective than THC or CBD for regulating the functions that support the endocannabinoid system while reducing pain caused by inflammation. It is well known that THC and CBD are effective for improving mood in response to physical pain, however they do a little to influence the causes of pain or systemic disease in comparison to CBDA. Patients that use CBDA prefer it to CBD or THC for long-term synergistic benefits that restore health and wellness which influences mood.
CBDA influence the human endocannabinoid system and not the CB1 receptors. CBDA reguialtes inflammation in the Endo cannabinoid system by regualting the 4 enzymens that give rise to inflammation
CBDA has been shown to modulate the autonomic nervous system, the auto immune system, and microcirculation. It is known to relieve pain due to inflammation and to have anti-convulsant, anti-spasmodic, and antioxidant properties. It is reported to be immune supportive and be anti-proliferative (anticancer) however, clinical results are currently unavailable.
It is known to be used internally as a digestive or as a suppository for infirmed patients.
It may be used as a topical for sore muscles, bruising, insect bites, rashes, mild abrasions, and certain skin conditions.
It is known to be compatible with other cannabinoids including THC, CBD, CBN, and CBG.
Publications and lectures of Professor Raphael Mechoulam PhD. His main contributions are in the field of the constituents of cannabis and the endogenous cannabinoids found in the brain and the periphery.
Lectures of William Courtney, MD. His main contributions are in the field of uses of THCA in the form of raw juiced cannabis for treatment of diseases.
Medical Acids Cannabinoids, United States Patent Number US 7,807,710 B2
Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb
Review by Cell Press, 2009, Download PDF below.
D9-THC, CBD, CBG, CBC, D9-THCA and CBDA have been shown to exert anti-proliferative/pro-apoptotic effects (IC50 in the range 5–25 mM) in a panel of tumor cell lines: human breast carcinoma, human prostate carcinoma, human colorectal carcinoma, human gastric adeno carcinoma, C6 rat glioma, rat basophilic leukemia and transformed thyroid cells. CBD exhibited the highest potency with IC50 values between 6 mM and 10.6 mM, and maximal efficacy at 25 mM, followed by CBG and CBC . CBDA was the least effective compound, being active against only breast, thyroid and glioma cells. Furthermore, prostate carcinoma cells were found to be quite resistant to the action of phytocannabinoids, with only CBD and CBG exerting anti-proliferative effects . More in-depth studies showed that CBD inhibited glioma, leukemia and breast cancer, as detailed below.
Take a look at what medical benefits THCA has and the benefits of THC in the acid form which is non-psychoactive.
How to convert raw cannabis into a medical grade TCHA standard adult dose in a digestible tincture using ethanol/alcohol as a solvent.