Since 2009, CBD Science has provided Consulting, Research and Education to the Cannabis and Hemp Industries. CBD Science does not offer medical advice. It provides services grounded in the Science of “Synergistics”” as articulated by R. Buckminster Fuller.
We employ Fuller’s visionary Synergistic Geometry to understand Phytocannabinoiods and their interaction with the Endo Cannabinoid System (ECS), In 2011, we provided the CBD tinctures to the team at Harborside Health Center that successfully treated the first case of Dravets syndrome (seizures) in a 4-year-old boy named Jayden.
CBD Science provides fact-based information about Phyto cannabinoids and their interactions with our Endo Cannabinoid Systems (ECS). Phyto cannabinoids are the natural medicinally active chemicals compound in Cannabis Sativa plant. Of the 120 cannabinoids thus far isolated, THC and CBD have gained the most attention. Despite the tons of existing research there remains a fundamental misunderstanding of how both THC and CBD operate. An innoviated understanding of how they operate can be found in out paper “Yin/Yang..Excerpts from the CBD Science Guide to Medical Marijuana”
CBD is psychoactive
It is a “indirect antagonist” of the CB1 receptor. That means it reduces mental activity. Therefore it is De activating. That is why people take it for anxiety, It also increases Anadamine, the endocannabinoid that is responsible for for what is called the “runners’ high”
THC and CBD operate as Yin and Yang for mental activity on the CB1 receptor.
THC is a Direct agonist of the CB1 receptor. It increases mental activity generated by the CB1 receptor
CBD is an Indirect Antagonist of the CB1 receptor …it decreases mental activity generated by the CB1 receptor
Both THC and CBD are Biphasic
Euphoria generated by THC will turn into Paranoia if you take too much
Calm generated by CBD will turn into Anxiety if you take too much.
Say’s who? Rafael Mechoulam, the person who discovered CBD and THC.
Raphael’s work has been replicated
Both THC and CBD can trigger mental “Cannabis intoxication”
Too much THC generates “too much thinking” i.e. conspiracy theories
Too much CBD generates “not enough thinking” signs of dementia
Here is a research report that details the “mechanism of operations” for both THC and CBD
CBD and THC are not Anti-inflammatory
The research paper entitled “Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids isolated from Cannabis Sativa” published on Pub Med by NIH reveals that CBD and THC by themselves are neutral to negative for inflammation https://www.ncbi.nlm.nih.gov/pubmed/21532172.
Users experience minor anti-inflammatory relief if they take it orally because the second metabolite of CBD (CH-COOH-CBD), and THC (CH-COOH-THC) are anti-inflammatory.
Users seeking anti-inflammatory Relief should take CBDA. CBDA is 100 times more anti-inflammatory than CBD. The mechanism of action is detailed in the following patent https://patents.google.com/patent/US7807711B2/en
US Patent #70807711 “Medicinal Acidic Cannabinoids This patent reveals how the acidic cannabinoids regulate the 4 enzyme that trigger inflammation COX-1, COX-2, TNF(a) and Interluten 10, that give rise to inflammation and they do so without hurting you stomach
Of the 120 cannabinoids thus far isolated, THC and CBD have gained the most attention. Despite the tons of existing research there remains a fundamental misunderstanding of how both THC and CBD operate.
UNDERSTANDING THE LIFE CYCLE OF PHYTOCANNABINOID PRODUCTION
Cannabinoids are chemical molecular compounds found naturally in cannabis and hemp. They are produced in three stages throughout the life cycle of the plants. Specific strains produce greater percentages of varieties of currently known beneficial cannabinoids. CBD Science harvests specific cannabinoid at specific stages for specific formulations based proven effects of cannabinoids on receptors associated with the endocannabinoid system.
STAGES OF THE PLANT
Early Stage: The young plant produces cannabinoids that are the building blocks for growth to maturity including: THCA, THCVA, CBGA, CBGVA, CBDA, CBDVA, CBCA and CBCVA. The “A” in each refers the cannabinoid as an acid and in a raw or unheated state. This class of cannabinoids are associated with plant growth.
Middle Stage: The mature plant produces cannabinoids that maintain vitality for flowering, fertilization, and seed production including: THC, THCV, CBG, CBGV, CBD, CBDV, CBC and CBCV. Through the process of heating, acidic molecular compounds loose one molecule. The converted compound effects cellular receptor differently than acidic cannabinoids. This class of cannabinoids is associated with the regulation of a healthy plant.
Late Stage: The aging plant produces cannabinoids that shut down growth. It terminates seed production and effectively puts the plant to sleep by producing CBN and CBL.